STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGFRL1Putative fibroblast growth factor receptor-like 1-like. (463 aa)    
Predicted Functional Partners:
SMAX5B_008758
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.899
SMAX5B_010598
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.863
ENSSMAP00000009492
annotation not available
    
 0.853
SMAX5B_006700
Growth factor receptor-bound protein 2.
   
 0.852
ENSSMAP00000032474
Fibroblast growth factor receptor substrate 2b.
    
 0.824
SMAX5B_002378
Putative fibroblast growth factor receptor substrate 2-like.
    
 0.824
SMAX5B_019386
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
    
 0.813
SMAX5B_008888
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
    
 0.813
SMAX5B_008835
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.811
SMAX5B_019227
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.811
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.