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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSMAP00000003733Activity-dependent neuroprotector homeobox b. (1069 aa)    
Predicted Functional Partners:
SMAX5B_010186
Putative E3 ubiquitin-protein ligase TRIP12-like isoform 2.
   
  
 0.664
CHD8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]
   
 
 0.660
ENSSMAP00000010564
Chromodomain helicase DNA binding protein 3.
   
 
 0.647
ENSSMAP00000018351
Chromodomain helicase DNA binding protein 4b.
   
 
 0.647
ENSSMAP00000020865
Chromodomain helicase DNA binding protein 4a.
   
 
 0.647
ENSSMAP00000029345
annotation not available
   
 
 0.647
SMAX5B_006000
Putative nucleosome-remodeling factor subunit BPTF-like.
   
  
 0.637
SMAX5B_007455
Putative nucleosome-remodeling factor subunit BPTF isoform 2.
   
  
 0.637
ENSSMAP00000007459
Chromobox homolog 5 (HP1 alpha homolog, Drosophila).
    
 
 0.613
CBX1
Putative chromobox protein-like 1 isoform 2.
    
 
 0.613
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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