| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SMAX5B_000441 | SMAX5B_001062 | ENSSMAP00000031898 | ENSSMAP00000020033 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Putative AT-rich interactive domain-containing protein 4A isoform 2. | 0.683 |
| SMAX5B_000441 | SMAX5B_003989 | ENSSMAP00000031898 | ENSSMAP00000012049 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | H2AFY MGC137823 isoform 3; Belongs to the histone H2A family. | 0.670 |
| SMAX5B_000441 | SMAX5B_003997 | ENSSMAP00000031898 | ENSSMAP00000000241 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Putative nuclear receptor corepressor 1 isoform 2. | 0.409 |
| SMAX5B_000441 | SMAX5B_007100 | ENSSMAP00000031898 | ENSSMAP00000003880 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Histone deacetylase. | 0.915 |
| SMAX5B_000441 | SMAX5B_008496 | ENSSMAP00000031898 | ENSSMAP00000026848 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | 0.670 |
| SMAX5B_000441 | SMAX5B_016138 | ENSSMAP00000031898 | ENSSMAP00000019955 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Uncharacterized protein. | 0.663 |
| SMAX5B_000441 | SMAX5B_016772 | ENSSMAP00000031898 | ENSSMAP00000016807 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Histone deacetylase complex subunit SAP30L. | 0.691 |
| SMAX5B_000441 | SMAX5B_016833 | ENSSMAP00000031898 | ENSSMAP00000016989 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Putative AT-rich interactive domain-containing protein 4B isoform 2. | 0.683 |
| SMAX5B_001062 | SMAX5B_000441 | ENSSMAP00000020033 | ENSSMAP00000031898 | Putative AT-rich interactive domain-containing protein 4A isoform 2. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.683 |
| SMAX5B_001062 | SMAX5B_003989 | ENSSMAP00000020033 | ENSSMAP00000012049 | Putative AT-rich interactive domain-containing protein 4A isoform 2. | H2AFY MGC137823 isoform 3; Belongs to the histone H2A family. | 0.707 |
| SMAX5B_001062 | SMAX5B_004320 | ENSSMAP00000020033 | ENSSMAP00000026179 | Putative AT-rich interactive domain-containing protein 4A isoform 2. | Putative short transient receptor potential channel 2-like; Belongs to the transient receptor (TC 1.A.4) family. | 0.941 |
| SMAX5B_001062 | SMAX5B_007100 | ENSSMAP00000020033 | ENSSMAP00000003880 | Putative AT-rich interactive domain-containing protein 4A isoform 2. | Histone deacetylase. | 0.956 |
| SMAX5B_001062 | SMAX5B_008496 | ENSSMAP00000020033 | ENSSMAP00000026848 | Putative AT-rich interactive domain-containing protein 4A isoform 2. | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. | 0.707 |
| SMAX5B_001062 | SMAX5B_016138 | ENSSMAP00000020033 | ENSSMAP00000019955 | Putative AT-rich interactive domain-containing protein 4A isoform 2. | Uncharacterized protein. | 0.996 |
| SMAX5B_001062 | SMAX5B_016772 | ENSSMAP00000020033 | ENSSMAP00000016807 | Putative AT-rich interactive domain-containing protein 4A isoform 2. | Histone deacetylase complex subunit SAP30L. | 0.996 |
| SMAX5B_001062 | SMAX5B_016833 | ENSSMAP00000020033 | ENSSMAP00000016989 | Putative AT-rich interactive domain-containing protein 4A isoform 2. | Putative AT-rich interactive domain-containing protein 4B isoform 2. | 0.752 |
| SMAX5B_003989 | SMAX5B_000441 | ENSSMAP00000012049 | ENSSMAP00000031898 | H2AFY MGC137823 isoform 3; Belongs to the histone H2A family. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.670 |
| SMAX5B_003989 | SMAX5B_001062 | ENSSMAP00000012049 | ENSSMAP00000020033 | H2AFY MGC137823 isoform 3; Belongs to the histone H2A family. | Putative AT-rich interactive domain-containing protein 4A isoform 2. | 0.707 |
| SMAX5B_003989 | SMAX5B_007100 | ENSSMAP00000012049 | ENSSMAP00000003880 | H2AFY MGC137823 isoform 3; Belongs to the histone H2A family. | Histone deacetylase. | 0.904 |
| SMAX5B_003989 | SMAX5B_012522 | ENSSMAP00000012049 | ENSSMAP00000023325 | H2AFY MGC137823 isoform 3; Belongs to the histone H2A family. | Putative RNA polymerase-associated protein LEO1-like. | 0.767 |