close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_012565Wilms' tumor suppressor 1b isoform 2. (425 aa)    
Predicted Functional Partners:
SMAX5B_019619
Putative adenylate kinase 9 isoform 2.
    
  0.873
SMAX5B_001446
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.692
SMAX5B_018326
Putative BRCA1-associated RING domain protein 1 isoform 2.
    
 0.691
SMAX5B_007298
Uncharacterized protein.
   
  0.680
SMAX5B_019586
Putative pre-mRNA-splicing regulator WTAP.
    
 
 0.680
SMAX5B_004819
Putative receptor-interacting serine/threonine-protein kinase 4.
    
 0.634
SMAX5B_021260
Zf-C4 domain containing protein.
   
 0.631
SMAX5B_022600
Putative nuclear receptor subfamily 5 group A member 2.
   
 0.631
SMAX5B_001802
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.597
YTHDC2
Putative ATP-dependent RNA helicase YTHDC2.
    
  0.581
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
Server load: low (40%) [HD]