| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SMAX5B_000212 | SMAX5B_001039 | ENSSMAP00000007673 | ENSSMAP00000024622 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Putative antithrombin-III; Belongs to the serpin family. | 0.975 |
| SMAX5B_000212 | SMAX5B_002120 | ENSSMAP00000007673 | ENSSMAP00000000080 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.938 |
| SMAX5B_000212 | SMAX5B_003580 | ENSSMAP00000007673 | ENSSMAP00000032336 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Uncharacterized protein. | 0.912 |
| SMAX5B_000212 | SMAX5B_003682 | ENSSMAP00000007673 | ENSSMAP00000032357 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. | 0.912 |
| SMAX5B_000212 | SMAX5B_006646 | ENSSMAP00000007673 | ENSSMAP00000014489 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Putative alpha-2-HS-glycoprotein isoform 2. | 0.909 |
| SMAX5B_000212 | SMAX5B_009673 | ENSSMAP00000007673 | ENSSMAP00000006771 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Putative alpha-2-HS-glycoprotein-like. | 0.909 |
| SMAX5B_000212 | SMAX5B_011451 | ENSSMAP00000007673 | ENSSMAP00000002908 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Putative fibrinogen gamma chain. | 0.956 |
| SMAX5B_000212 | SMAX5B_015271 | ENSSMAP00000007673 | ENSSMAP00000004012 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. | 0.860 |
| SMAX5B_001039 | SMAX5B_000212 | ENSSMAP00000024622 | ENSSMAP00000007673 | Putative antithrombin-III; Belongs to the serpin family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.975 |
| SMAX5B_001039 | SMAX5B_002120 | ENSSMAP00000024622 | ENSSMAP00000000080 | Putative antithrombin-III; Belongs to the serpin family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.999 |
| SMAX5B_001039 | SMAX5B_003580 | ENSSMAP00000024622 | ENSSMAP00000032336 | Putative antithrombin-III; Belongs to the serpin family. | Uncharacterized protein. | 0.882 |
| SMAX5B_001039 | SMAX5B_003682 | ENSSMAP00000024622 | ENSSMAP00000032357 | Putative antithrombin-III; Belongs to the serpin family. | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. | 0.882 |
| SMAX5B_001039 | SMAX5B_006646 | ENSSMAP00000024622 | ENSSMAP00000014489 | Putative antithrombin-III; Belongs to the serpin family. | Putative alpha-2-HS-glycoprotein isoform 2. | 0.833 |
| SMAX5B_001039 | SMAX5B_009673 | ENSSMAP00000024622 | ENSSMAP00000006771 | Putative antithrombin-III; Belongs to the serpin family. | Putative alpha-2-HS-glycoprotein-like. | 0.833 |
| SMAX5B_001039 | SMAX5B_011451 | ENSSMAP00000024622 | ENSSMAP00000002908 | Putative antithrombin-III; Belongs to the serpin family. | Putative fibrinogen gamma chain. | 0.954 |
| SMAX5B_001039 | SMAX5B_015271 | ENSSMAP00000024622 | ENSSMAP00000004012 | Putative antithrombin-III; Belongs to the serpin family. | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. | 0.885 |
| SMAX5B_002120 | SMAX5B_000212 | ENSSMAP00000000080 | ENSSMAP00000007673 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.938 |
| SMAX5B_002120 | SMAX5B_001039 | ENSSMAP00000000080 | ENSSMAP00000024622 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Putative antithrombin-III; Belongs to the serpin family. | 0.999 |
| SMAX5B_002120 | SMAX5B_003580 | ENSSMAP00000000080 | ENSSMAP00000032336 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Uncharacterized protein. | 0.946 |
| SMAX5B_002120 | SMAX5B_003682 | ENSSMAP00000000080 | ENSSMAP00000032357 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. | 0.946 |
STRING v12.5 is now available!
