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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSMAP00000004467REST corepressor 1. (437 aa)    
Predicted Functional Partners:
SMAX5B_000441
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 0.977
KDM1B
Putative lysine-specific histone demethylase 1B.
   
 0.907
SMAX5B_004766
Amine oxidase.
   
 0.902
SMAX5B_015075
Putative flavin-containing monoamine oxidase A.
   
 0.902
SMAX5B_022363
High mobility group 20B.
   
 0.885
SMAX5B_003473
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.884
ENSSMAP00000031618
PHD finger protein 21Ab.
   
 0.884
SMAX5B_016328
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.884
SMAX5B_014980
Putative zinc finger protein 217 isoform 2.
    
 0.829
ENSSMAP00000010564
Chromodomain helicase DNA binding protein 3.
    
 0.828
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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