close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tlr5-bToll-like receptor 5 membrane form; Belongs to the Toll-like receptor family. (892 aa)    
Predicted Functional Partners:
SMAX5B_001941
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.955
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.895
SMAX5B_004958
Uncharacterized protein.
    
 0.880
SMAX5B_000685
Putative toll/interleukin-1 receptor domain-containing adapter protein.
   
 0.825
SMAX5B_017229
Uncharacterized protein.
   
 0.815
SMAX5B_021142
NF-kappaB 2.
   
 0.815
SMAX5B_007298
Uncharacterized protein.
    
  0.774
SMAX5B_013308
Putative transcription factor RelB.
   
 0.751
SMAX5B_001352
P65 transcription factor.
   
 0.751
REL
C-rel.
   
 0.751
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.