close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_001287Putative E3 ubiquitin-protein ligase RFWD3. (692 aa)    
Predicted Functional Partners:
ENSSMAP00000028620
Replication protein A3.
    
 
 0.979
SMAX5B_011489
Putative DNA-directed primase/polymerase protein.
    
   0.965
SMAX5B_009864
Putative replication protein A 70 kDa DNA-binding subunit.
   
 
 0.913
RPA1
Replication protein A1.
   
 
 0.913
SMAX5B_020184
Putative meiosis-specific with OB domain-containing protein.
   
 
 0.836
SMAX5B_000852
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
    
 
 0.709
ENSSMAP00000003427
annotation not available
    
 
 0.709
SMAX5B_012149
Putative replication protein A 32 kDa subunit.
    
 
 0.709
SMAX5B_016269
Putative replication protein A 32 kDa subunit-like isoform 4.
    
 
 0.709
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
    
 
 0.691
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
Server load: low (24%) [HD]