ENSSMAP00000005189 protein (Scophthalmus maximus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ENSSMAP00000005189

annotation not available (450 aa)

Predicted Functional Partners:

SMAX5B_001446

0.818

DCAF7

0.709

SMAX5B_015688

0.697

SMAX5B_015982

0.682

SMAX5B_019272

0.639

SMAX5B_005752

0.628

ENSSMAP00000020441

0.628

SMAX5B_006291

0.615

SMAX5B_020257

0.615

ENSSMAP00000000393

0.601

Your Current Organism:

Scophthalmus maximus

NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCAF7	ENSSMAP00000005189	ENSSMAP00000014526	ENSSMAP00000005189	DDB1-and CUL4-associated factor 7.	annotation not available	0.709
ENSSMAP00000000393	ENSSMAP00000005189	ENSSMAP00000000393	ENSSMAP00000005189	Peptidylprolyl cis/trans isomerase, NIMA-interacting 1.	annotation not available	0.601
ENSSMAP00000000393	SMAX5B_001446	ENSSMAP00000000393	ENSSMAP00000015064	Peptidylprolyl cis/trans isomerase, NIMA-interacting 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.989
ENSSMAP00000005189	DCAF7	ENSSMAP00000005189	ENSSMAP00000014526	annotation not available	DDB1-and CUL4-associated factor 7.	0.709
ENSSMAP00000005189	ENSSMAP00000000393	ENSSMAP00000005189	ENSSMAP00000000393	annotation not available	Peptidylprolyl cis/trans isomerase, NIMA-interacting 1.	0.601
ENSSMAP00000005189	ENSSMAP00000020441	ENSSMAP00000005189	ENSSMAP00000020441	annotation not available	Ubiquitin-conjugating enzyme E2Ia.	0.628
ENSSMAP00000005189	SMAX5B_001446	ENSSMAP00000005189	ENSSMAP00000015064	annotation not available	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.818
ENSSMAP00000005189	SMAX5B_005752	ENSSMAP00000005189	ENSSMAP00000012316	annotation not available	Putative SUMO-conjugating enzyme UBC9 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.	0.628
ENSSMAP00000005189	SMAX5B_006291	ENSSMAP00000005189	ENSSMAP00000010015	annotation not available	Putative histone acetyltransferase p300-like isoform 2.	0.615
ENSSMAP00000005189	SMAX5B_015688	ENSSMAP00000005189	ENSSMAP00000028503	annotation not available	Putative death domain-associated protein 6.	0.697
ENSSMAP00000005189	SMAX5B_015982	ENSSMAP00000005189	ENSSMAP00000002013	annotation not available	Small ubiquitin-related modifier.	0.682
ENSSMAP00000005189	SMAX5B_019272	ENSSMAP00000005189	ENSSMAP00000013005	annotation not available	Putative E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.639
ENSSMAP00000005189	SMAX5B_020257	ENSSMAP00000005189	ENSSMAP00000010755	annotation not available	Putative histone acetyltransferase p300-like.	0.615
ENSSMAP00000020441	ENSSMAP00000005189	ENSSMAP00000020441	ENSSMAP00000005189	Ubiquitin-conjugating enzyme E2Ia.	annotation not available	0.628
ENSSMAP00000020441	SMAX5B_001446	ENSSMAP00000020441	ENSSMAP00000015064	Ubiquitin-conjugating enzyme E2Ia.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.946
ENSSMAP00000020441	SMAX5B_005752	ENSSMAP00000020441	ENSSMAP00000012316	Ubiquitin-conjugating enzyme E2Ia.	Putative SUMO-conjugating enzyme UBC9 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.	0.900
ENSSMAP00000020441	SMAX5B_006291	ENSSMAP00000020441	ENSSMAP00000010015	Ubiquitin-conjugating enzyme E2Ia.	Putative histone acetyltransferase p300-like isoform 2.	0.766
ENSSMAP00000020441	SMAX5B_015688	ENSSMAP00000020441	ENSSMAP00000028503	Ubiquitin-conjugating enzyme E2Ia.	Putative death domain-associated protein 6.	0.954
ENSSMAP00000020441	SMAX5B_015982	ENSSMAP00000020441	ENSSMAP00000002013	Ubiquitin-conjugating enzyme E2Ia.	Small ubiquitin-related modifier.	0.992
ENSSMAP00000020441	SMAX5B_019272	ENSSMAP00000020441	ENSSMAP00000013005	Ubiquitin-conjugating enzyme E2Ia.	Putative E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.650