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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_002555R-spondin-1. (282 aa)    
Predicted Functional Partners:
ENSSMAP00000000637
annotation not available
   
 0.994
ENSSMAP00000021125
Zinc and ring finger 3.
   
 0.993
SMAX5B_012713
Leucine-rich repeat-containing G protein-coupled receptor 4-like.
  
 0.986
LGR5
Putative leucine-rich repeat-containing G-protein coupled receptor 5.
  
 0.984
LGR6
Putative leucine-rich repeat-containing G-protein coupled receptor 6-like.
    
 0.952
SMAX5B_008071
Putative R-spondin-2-like.
  
  
0.861
SMAX5B_006057
Putative E3 ubiquitin-protein ligase RNF126-like isoform 2.
   
 0.858
ENSSMAP00000004251
Si:ch211-81a5.1.
   
 0.858
RNF126
Ring finger protein 126.
   
 0.858
ENSSMAP00000023279
Ring finger protein 215.
   
 0.858
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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