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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSMAP00000006578Adenylate cyclase 2a. (1210 aa)    
Predicted Functional Partners:
SMAX5B_010440
Phosphodiesterase.
   
 0.878
SMAX5B_005793
Phosphodiesterase.
   
 0.878
SMAX5B_022266
Putative cAMP-specific 3'-5'-cyclic phosphodiesterase 4B-like.
   
 0.878
SMAX5B_002356
Guanine nucleotide-binding protein G(I) subunit alpha-2.
   
 0.876
ENSSMAP00000027797
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
   
 0.876
SMAX5B_014613
Guanine nucleotide-binding protein G(K) subunit alpha.
   
 0.876
SMAX5B_012542
Phosphodiesterase.
   
 0.875
SMAX5B_020028
Phosphodiesterase.
   
 0.872
SMAX5B_009164
Phosphodiesterase.
   
 0.872
PDE7B
Phosphodiesterase.
   
 0.872
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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