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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_009620Putative spindle assembly abnormal protein 6-like. (591 aa)    
Predicted Functional Partners:
SMAX5B_000328
Putative Fanconi anemia group M protein.
   
 0.976
SMAX5B_015882
MHC class Ia chain isoform 2; Belongs to the MHC class I family.
   
 0.934
SMAX5B_006077
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.929
ENSSMAP00000028620
Replication protein A3.
   
 0.927
SMAX5B_017976
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
   
 0.915
SMAX5B_016376
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.908
SMAX5B_021992
Putative serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.
   
 0.905
SMAX5B_016507
Putative recQ-mediated genome instability protein 1.
   
 0.901
SMAX5B_010091
Putative DNA repair protein RAD52-like.
    
 0.899
SMAX5B_009864
Putative replication protein A 70 kDa DNA-binding subunit.
   
 0.896
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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