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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_017761Putative E3 SUMO-protein ligase EGR2-like. (409 aa)    
Predicted Functional Partners:
SMAX5B_019619
Putative adenylate kinase 9 isoform 2.
    
  0.873
SMAX5B_016703
Putative E3 SUMO-protein ligase EGR2.
  
 
 
0.857
SMAX5B_010984
Uncharacterized protein.
  
 
 
0.856
SMAX5B_008861
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
    
 
0.829
SMAX5B_007298
Uncharacterized protein.
   
  0.680
SMAX5B_018326
Putative BRCA1-associated RING domain protein 1 isoform 2.
    
 0.636
SMAX5B_004819
Putative receptor-interacting serine/threonine-protein kinase 4.
    
  0.633
SMAX5B_001802
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.597
FOXJ3
Putative forkhead box protein J3-like.
    
 0.582
YTHDC2
Putative ATP-dependent RNA helicase YTHDC2.
    
  0.581
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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