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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSMAP00000007052Si:dkey-32e6.3. (379 aa)    
Predicted Functional Partners:
CUL3
Cullin-3; Belongs to the cullin family.
    
 0.597
SMAX5B_009686
Cullin-1; Belongs to the cullin family.
    
 0.597
SMAX5B_008761
Putative myopalladin; Belongs to the cullin family.
    
 0.597
SMAX5B_003815
Cullin-3; Belongs to the cullin family.
    
 0.597
SMAX5B_018172
NEDD8-conjugating enzyme UBE2F isoform 2; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.574
SMAX5B_012379
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
     
 0.502
SMAX5B_006467
Putative RING-box protein 1-like.
    
 0.475
SMAX5B_010176
Putative RING-box protein 2-like isoform 3.
    
 0.475
SMAX5B_001624
Uncharacterized protein.
    
  0.419
SMAX5B_001548
COP9 signalosome complex subunit 5.
    
  0.419
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.