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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSHR-2Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (725 aa)    
Predicted Functional Partners:
SMAX5B_005648
Follicle-stimulating hormone beta subunit.
   
 0.937
SMAX5B_013628
Thyrotropin subunit beta.
    
 0.902
TSHB
Putative thyrotropin subunit beta-like.
    
 0.900
LHbeta
Luteinizing hormone beta subunit isoform 3.
   
 0.899
SMAX5B_007298
Uncharacterized protein.
   
 
  0.846
SMAX5B_002555
R-spondin-1.
    
 0.800
SMAX5B_008071
Putative R-spondin-2-like.
    
 0.780
ENSSMAP00000013306
R-spondin 2.
    
 0.775
SMAX5B_012183
Uncharacterized protein.
    
 0.772
SMAX5B_000530
Natriuretic peptide.
   
 
  0.761
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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