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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_007979Putative corticosteroid 11-beta-dehydrogenase isozyme 2. (232 aa)    
Predicted Functional Partners:
SMAX5B_011748
Putative cytochrome P450 11B mitochondrial-like; Belongs to the cytochrome P450 family.
   
 
 0.916
SMAX5B_011796
Putative tenascin-X.
   
 
 0.886
SMAX5B_010060
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
   
 
 0.874
SMAX5B_001133
Putative 3 beta-hydroxysteroid dehydrogenase/Delta 5--4-isomerase type 1; Belongs to the 3-beta-HSD family.
     
 0.859
SMAX5B_008545
Steroid 17-alpha-hydroxylase/17-20 lyase.
   
 
 0.856
SMAX5B_004462
CYP17II 17-alpha-hydroxylase; Belongs to the cytochrome P450 family.
   
 
 0.856
SMAX5B_022506
Putative hydroxysteroid 11-beta-dehydrogenase 1-like protein.
   
 
 0.848
AKR1D1
3-oxo-5-beta-steroid 4-dehydrogenase isoform 4.
   
 
 0.839
SMAX5B_005495
Aldo-keto reductase family 1 member D1 (Delta 4-3-ketosteroid-5-beta-reductase) isoform 2.
   
 
 0.839
SMAX5B_011176
Putative 3 beta-hydroxysteroid dehydrogenase type 7; Belongs to the 3-beta-HSD family.
     
 0.838
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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