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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_008266Alpha-1-antitrypsin; Belongs to the serpin family. (480 aa)    
Predicted Functional Partners:
SMAX5B_002120
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
 0.934
SMAX5B_001039
Putative antithrombin-III; Belongs to the serpin family.
  
0.755
SMAX5B_008134
Putative glutaredoxin-related protein 5 mitochondrial.
   
 0.719
ENSSMAP00000011455
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.
  
 
0.703
SMAX5B_004485
Fibrinogen beta chain isoform 2.
   
 0.699
SMAX5B_013447
Putative vitronectin.
   
 0.693
SMAX5B_012733
Putative vitronectin-like.
   
 0.677
SMAX5B_007149
Putative low-density lipoprotein receptor-related protein 5.
    
 0.674
SMAX5B_017501
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.674
SMAX5B_001485
Putative hepatocyte growth factor activator.
  
 0.660
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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