SMAX5B_000212 protein (Scophthalmus maximus)

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SMAX5B_000212

Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (754 aa)

Predicted Functional Partners:

SMAX5B_004485

0.982

SMAX5B_018875

0.978

SMAX5B_001039

0.975

ENSSMAP00000011455

0.969

ENSSMAP00000027798

0.964

SMAX5B_004442

0.964

SMAX5B_011451

0.956

SMAX5B_002120

0.938

SMAX5B_001485

0.930

SMAX5B_003580

0.912

Your Current Organism:

Scophthalmus maximus

NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSMAP00000011455	ENSSMAP00000027798	ENSSMAP00000011455	ENSSMAP00000027798	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	annotation not available	0.870
ENSSMAP00000011455	SMAX5B_000212	ENSSMAP00000011455	ENSSMAP00000007673	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.969
ENSSMAP00000011455	SMAX5B_001039	ENSSMAP00000011455	ENSSMAP00000024622	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	Putative antithrombin-III; Belongs to the serpin family.	0.876
ENSSMAP00000011455	SMAX5B_001485	ENSSMAP00000011455	ENSSMAP00000015745	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	Putative hepatocyte growth factor activator.	0.713
ENSSMAP00000011455	SMAX5B_002120	ENSSMAP00000011455	ENSSMAP00000000080	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.998
ENSSMAP00000011455	SMAX5B_003580	ENSSMAP00000011455	ENSSMAP00000032336	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	Uncharacterized protein.	0.632
ENSSMAP00000011455	SMAX5B_004442	ENSSMAP00000011455	ENSSMAP00000027830	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	Putative fibrinogen alpha chain-like.	0.870
ENSSMAP00000011455	SMAX5B_004485	ENSSMAP00000011455	ENSSMAP00000027789	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	Fibrinogen beta chain isoform 2.	0.919
ENSSMAP00000011455	SMAX5B_011451	ENSSMAP00000011455	ENSSMAP00000002908	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	Putative fibrinogen gamma chain.	0.917
ENSSMAP00000011455	SMAX5B_018875	ENSSMAP00000011455	ENSSMAP00000020760	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	Putative alpha-2-antiplasmin-like isoform 2; Belongs to the serpin family.	0.565
ENSSMAP00000027798	ENSSMAP00000011455	ENSSMAP00000027798	ENSSMAP00000011455	annotation not available	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.	0.870
ENSSMAP00000027798	SMAX5B_000212	ENSSMAP00000027798	ENSSMAP00000007673	annotation not available	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.964
ENSSMAP00000027798	SMAX5B_001039	ENSSMAP00000027798	ENSSMAP00000024622	annotation not available	Putative antithrombin-III; Belongs to the serpin family.	0.951
ENSSMAP00000027798	SMAX5B_001485	ENSSMAP00000027798	ENSSMAP00000015745	annotation not available	Putative hepatocyte growth factor activator.	0.542
ENSSMAP00000027798	SMAX5B_002120	ENSSMAP00000027798	ENSSMAP00000000080	annotation not available	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.997
ENSSMAP00000027798	SMAX5B_003580	ENSSMAP00000027798	ENSSMAP00000032336	annotation not available	Uncharacterized protein.	0.825
ENSSMAP00000027798	SMAX5B_004442	ENSSMAP00000027798	ENSSMAP00000027830	annotation not available	Putative fibrinogen alpha chain-like.	0.508
ENSSMAP00000027798	SMAX5B_004485	ENSSMAP00000027798	ENSSMAP00000027789	annotation not available	Fibrinogen beta chain isoform 2.	0.998
ENSSMAP00000027798	SMAX5B_011451	ENSSMAP00000027798	ENSSMAP00000002908	annotation not available	Putative fibrinogen gamma chain.	0.999
ENSSMAP00000027798	SMAX5B_018875	ENSSMAP00000027798	ENSSMAP00000020760	annotation not available	Putative alpha-2-antiplasmin-like isoform 2; Belongs to the serpin family.	0.844

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