STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_010951Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (286 aa)    
Predicted Functional Partners:
SMAX5B_006746
Putative MLN64 N-terminal domain-like.
 
   
 0.981
SMAX5B_004014
Voltage-dependent anion-selective channel protein 1.
     
 0.925
SMAX5B_011219
Putative stAR-related lipid transfer protein 3.
     
0.831
SMAX5B_010060
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
   
 
 0.831
SMAX5B_011748
Putative cytochrome P450 11B mitochondrial-like; Belongs to the cytochrome P450 family.
   
 
 0.829
SMAX5B_008005
Putative zinc finger protein 479-like.
    
 0.795
SMAX5B_005216
Putative vesicle-associated membrane protein-associated protein B-like.
    
 0.795
SMAX5B_019108
Putative motile sperm domain-containing protein 1.
    
 0.795
SMAX5B_006453
Putative vesicle-associated membrane protein-associated protein A.
    
 0.795
VAPB
Putative vesicle-associated membrane protein-associated protein B/C-like.
    
 0.795
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.