STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_008164Mut MGC162238. (754 aa)    
Predicted Functional Partners:
SMAX5B_012438
Putative methylmalonyl-CoA epimerase mitochondrial isoform 2.
  
 
 0.961
SUCLG2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.959
SMAX5B_011577
Putative methylmalonic aciduria type A protein mitochondrial.
  
 
 0.940
ENSSMAP00000007498
annotation not available
  
 
 0.936
SUCLA2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.918
ACLY
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
   
 0.890
SMAX5B_017328
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
   
 0.890
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
   
 
 0.885
SMAX5B_014772
Citrate synthase; Belongs to the citrate synthase family.
    
 0.862
ENSSMAP00000017291
Dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex).
   
 
 0.852
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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