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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_018069Putative tissue-type plasminogen activator-like isoform 2; Belongs to the peptidase S1 family. (388 aa)    
Predicted Functional Partners:
SMAX5B_017559
Putative plasminogen activator inhibitor 1; Belongs to the serpin family.
  
 0.966
ENSSMAP00000017475
annotation not available
    
  0.884
ENSSMAP00000017542
Immunoglobulin heavy variable 1-4.
    
  0.884
SMAX5B_000212
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
  
0.868
SMAX5B_022102
Met proto-oncogene (Hepatocyte growth factor receptor)-like.
    
 0.808
SMAX5B_014380
Putative macrophage-stimulating protein receptor-like.
    
 0.808
SMAX5B_002292
Putative macrophage-stimulating protein receptor-like.
    
 0.808
SMAX5B_015601
Protein S100; Belongs to the S-100 family.
   
 0.767
SMAX5B_018875
Putative alpha-2-antiplasmin-like isoform 2; Belongs to the serpin family.
   
 0.762
SMAX5B_010168
Protease nexin 1; Belongs to the serpin family.
  
 0.743
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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