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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_014091Putative NGFI-A-binding protein 2. (495 aa)    
Predicted Functional Partners:
SMAX5B_016703
Putative E3 SUMO-protein ligase EGR2.
   
 0.910
SMAX5B_010984
Uncharacterized protein.
   
 0.821
SMAX5B_008861
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
   
 0.815
ENSSMAP00000010564
Chromodomain helicase DNA binding protein 3.
   
 0.765
ENSSMAP00000018351
Chromodomain helicase DNA binding protein 4b.
   
 0.765
ENSSMAP00000020865
Chromodomain helicase DNA binding protein 4a.
   
 0.765
ENSSMAP00000029345
annotation not available
   
 0.765
PHF21B
Putative PHD finger protein 21B.
   
 0.706
ENSSMAP00000031618
PHD finger protein 21Ab.
   
 0.706
SMAX5B_000283
Putative Krueppel-like factor 11.
    
 0.680
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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