SMAX5B_014026 protein (Scophthalmus maximus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SMAX5B_014026

Putative engulfment and cell motility protein 2-like. (743 aa)

Predicted Functional Partners:

SMAX5B_005409

0.983

ENSSMAP00000010333

0.910

SMAX5B_012243

0.910

SMAX5B_010986

0.889

SMAX5B_017453

0.889

DOCK2

0.889

SMAX5B_013053

0.880

SMAX5B_014736

0.880

SMAX5B_017268

0.842

SMAX5B_021490

0.811

Your Current Organism:

Scophthalmus maximus

NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DOCK2	ENSSMAP00000010333	ENSSMAP00000030866	ENSSMAP00000010333	Putative dedicator of cytokinesis protein 2; Belongs to the DOCK family.	Ras homolog gene family, member Gd.	0.823
DOCK2	SMAX5B_005409	ENSSMAP00000030866	ENSSMAP00000032617	Putative dedicator of cytokinesis protein 2; Belongs to the DOCK family.	Putative dedicator of cytokinesis protein 4-like; Belongs to the DOCK family.	0.652
DOCK2	SMAX5B_012243	ENSSMAP00000030866	ENSSMAP00000018044	Putative dedicator of cytokinesis protein 2; Belongs to the DOCK family.	Ras-like family member Gb.	0.823
DOCK2	SMAX5B_014026	ENSSMAP00000030866	ENSSMAP00000008926	Putative dedicator of cytokinesis protein 2; Belongs to the DOCK family.	Putative engulfment and cell motility protein 2-like.	0.889
DOCK2	SMAX5B_021490	ENSSMAP00000030866	ENSSMAP00000023007	Putative dedicator of cytokinesis protein 2; Belongs to the DOCK family.	Putative adapter molecule crk-like.	0.940
ENSSMAP00000010333	DOCK2	ENSSMAP00000010333	ENSSMAP00000030866	Ras homolog gene family, member Gd.	Putative dedicator of cytokinesis protein 2; Belongs to the DOCK family.	0.823
ENSSMAP00000010333	SMAX5B_005409	ENSSMAP00000010333	ENSSMAP00000032617	Ras homolog gene family, member Gd.	Putative dedicator of cytokinesis protein 4-like; Belongs to the DOCK family.	0.820
ENSSMAP00000010333	SMAX5B_010986	ENSSMAP00000010333	ENSSMAP00000002935	Ras homolog gene family, member Gd.	Putative dedicator of cytokinesis protein 5; Belongs to the DOCK family.	0.823
ENSSMAP00000010333	SMAX5B_013053	ENSSMAP00000010333	ENSSMAP00000008193	Ras homolog gene family, member Gd.	Putative dedicator of cytokinesis protein 3-like; Belongs to the DOCK family.	0.804
ENSSMAP00000010333	SMAX5B_014026	ENSSMAP00000010333	ENSSMAP00000008926	Ras homolog gene family, member Gd.	Putative engulfment and cell motility protein 2-like.	0.910
ENSSMAP00000010333	SMAX5B_014736	ENSSMAP00000010333	ENSSMAP00000015578	Ras homolog gene family, member Gd.	Putative dedicator of cytokinesis protein 3-like; Belongs to the DOCK family.	0.804
ENSSMAP00000010333	SMAX5B_017268	ENSSMAP00000010333	ENSSMAP00000005632	Ras homolog gene family, member Gd.	Putative clarin-3.	0.604
ENSSMAP00000010333	SMAX5B_017453	ENSSMAP00000010333	ENSSMAP00000005563	Ras homolog gene family, member Gd.	Putative dedicator of cytokinesis protein 1; Belongs to the DOCK family.	0.823
ENSSMAP00000010333	SMAX5B_021490	ENSSMAP00000010333	ENSSMAP00000023007	Ras homolog gene family, member Gd.	Putative adapter molecule crk-like.	0.563
SMAX5B_005409	DOCK2	ENSSMAP00000032617	ENSSMAP00000030866	Putative dedicator of cytokinesis protein 4-like; Belongs to the DOCK family.	Putative dedicator of cytokinesis protein 2; Belongs to the DOCK family.	0.652
SMAX5B_005409	ENSSMAP00000010333	ENSSMAP00000032617	ENSSMAP00000010333	Putative dedicator of cytokinesis protein 4-like; Belongs to the DOCK family.	Ras homolog gene family, member Gd.	0.820
SMAX5B_005409	SMAX5B_010986	ENSSMAP00000032617	ENSSMAP00000002935	Putative dedicator of cytokinesis protein 4-like; Belongs to the DOCK family.	Putative dedicator of cytokinesis protein 5; Belongs to the DOCK family.	0.653
SMAX5B_005409	SMAX5B_012243	ENSSMAP00000032617	ENSSMAP00000018044	Putative dedicator of cytokinesis protein 4-like; Belongs to the DOCK family.	Ras-like family member Gb.	0.820
SMAX5B_005409	SMAX5B_013053	ENSSMAP00000032617	ENSSMAP00000008193	Putative dedicator of cytokinesis protein 4-like; Belongs to the DOCK family.	Putative dedicator of cytokinesis protein 3-like; Belongs to the DOCK family.	0.750
SMAX5B_005409	SMAX5B_014026	ENSSMAP00000032617	ENSSMAP00000008926	Putative dedicator of cytokinesis protein 4-like; Belongs to the DOCK family.	Putative engulfment and cell motility protein 2-like.	0.983

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

14

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 103

1.39

2.4

8.86e-11

GO:0044238

Primary metabolic process

11 of 1033

0.43

0.36

0.0011

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 53

1.63

3.29

2.17e-11

GO:0070180

Large ribosomal subunit rRNA binding

2 of 2

2.4

1.09

0.0098

GO:0019843

rRNA binding

4 of 40

1.4

1.07

0.0029

GO:0003723

RNA binding

5 of 89

1.15

0.89

0.0029

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 56

1.61

3.29

6.22e-12

GO:0044391

Ribosomal subunit

5 of 14

1.96

3.18

6.49e-08

GO:0015934

Large ribosomal subunit

3 of 8

1.98

1.97

9.75e-05

GO:0015935

Small ribosomal subunit

2 of 6

1.93

1.24

0.0038

GO:0005622

Intracellular anatomical structure

11 of 972

0.46

0.4

0.00011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:103

Ribosomal protein

10 of 65

1.59

3.36

7.11e-13

CL:107

Ribosomal protein

9 of 58

1.6

3.22

8.40e-12

CL:110

Ribosomal protein

8 of 51

1.6

3.01

2.01e-10

CL:112

Ribosomal protein

7 of 45

1.6

2.71

7.76e-09

CL:155

Structural constituent of ribosome

4 of 16

1.8

2.07

2.61e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

9 of 55

1.62

3.32

6.37e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 40

1.65

2.76

1.68e-08

GOCC:0044391

Ribosomal subunit

4 of 16

1.8

2.09

2.30e-05

GOCC:0015935

Small ribosomal subunit

3 of 9

1.93

1.74

0.00028

GOCC:0043229

Intracellular organelle

10 of 270

0.97

1.14

9.78e-08

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 7

1.86

1.0

0.0114

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 54

1.63

3.33

8.02e-12

KW-0699

rRNA-binding

4 of 38

1.43

1.25

0.00083

KW-0810

Translation regulation

2 of 5

2.01

1.03

0.0108

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (18%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About