STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_002427Putative carboxypeptidase B2 isoform 2. (432 aa)    
Predicted Functional Partners:
SMAX5B_002120
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
 0.842
SMAX5B_015239
Putative complement C5; Belongs to the UDP-glycosyltransferase family.
   
 0.774
SMAX5B_002151
Putative coagulation factor VII-like.
  
 
 0.711
C8A
Putative complement component C8 alpha chain.
   
  
 0.683
SMAX5B_002105
Putative coagulation factor X.
  
 
 0.649
SMAX5B_002156
Putative coagulation factor X.
  
 
 0.649
SMAX5B_005368
Liver angiotensinogen isoform 2; Belongs to the serpin family.
   
 
  0.625
SMAX5B_000212
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
 
 0.620
ENSSMAP00000011455
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1.
   
 
 0.560
ENSSMAP00000016567
annotation not available
  
 
 0.546
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.