STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_011776Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (259 aa)    
Predicted Functional Partners:
SMAX5B_009276
Putative UBX domain-containing protein 1.
    
 0.995
SMAX5B_010521
Ubiquitin fusion degradation protein 1-like isoform 2.
   
 
 0.986
SMAX5B_003703
78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.
   
 0.983
SMAX5B_008147
Fibronectin type-II domain-containing protein.
   
 0.982
ENSSMAP00000006984
Proteasome 26S subunit, ATPase 1a.
     
 0.980
SMAX5B_011630
Putative NSFL1 cofactor p47.
    
 
 0.979
SMAX5B_014370
PRKCSH domain-containing protein.
    
 0.979
SMAX5B_017941
Putative endoplasmic reticulum lectin 1.
    
 0.979
SMAX5B_017038
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
0.977
SMAX5B_019337
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.977
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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