node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ITPA | SMAX5B_000426 | ENSSMAP00000028145 | ENSSMAP00000006209 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | 0.873 |
ITPA | SMAX5B_002418 | ENSSMAP00000028145 | ENSSMAP00000008790 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Peripheral plasma membrane protein CASK; Belongs to the MAGUK family. | 0.882 |
ITPA | SMAX5B_005914 | ENSSMAP00000028145 | ENSSMAP00000030732 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Putative guanylate kinase isoform 2. | 0.916 |
ITPA | SMAX5B_008178 | ENSSMAP00000028145 | ENSSMAP00000010751 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Putative ectonucleoside triphosphate diphosphohydrolase 5-like; Belongs to the GDA1/CD39 NTPase family. | 0.873 |
ITPA | SMAX5B_008208 | ENSSMAP00000028145 | ENSSMAP00000019202 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Nucleoside diphosphate kinase. | 0.911 |
ITPA | SMAX5B_011034 | ENSSMAP00000028145 | ENSSMAP00000012015 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Putative ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | 0.863 |
ITPA | SMAX5B_012364 | ENSSMAP00000028145 | ENSSMAP00000021145 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Putative bifunctional purine biosynthesis protein PURH. | 0.919 |
ITPA | SMAX5B_019619 | ENSSMAP00000028145 | ENSSMAP00000023479 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Putative adenylate kinase 9 isoform 2. | 0.923 |
ITPA | SMAX5B_021133 | ENSSMAP00000028145 | ENSSMAP00000012287 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Putative ectonucleoside triphosphate diphosphohydrolase 6 isoform 2; Belongs to the GDA1/CD39 NTPase family. | 0.860 |
ITPA | SMAX5B_022540 | ENSSMAP00000028145 | ENSSMAP00000006338 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Putative guanylate kinase-like. | 0.916 |
SMAX5B_000426 | ITPA | ENSSMAP00000006209 | ENSSMAP00000028145 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.873 |
SMAX5B_000426 | SMAX5B_002418 | ENSSMAP00000006209 | ENSSMAP00000008790 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Peripheral plasma membrane protein CASK; Belongs to the MAGUK family. | 0.825 |
SMAX5B_000426 | SMAX5B_005914 | ENSSMAP00000006209 | ENSSMAP00000030732 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Putative guanylate kinase isoform 2. | 0.842 |
SMAX5B_000426 | SMAX5B_008178 | ENSSMAP00000006209 | ENSSMAP00000010751 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Putative ectonucleoside triphosphate diphosphohydrolase 5-like; Belongs to the GDA1/CD39 NTPase family. | 0.845 |
SMAX5B_000426 | SMAX5B_008208 | ENSSMAP00000006209 | ENSSMAP00000019202 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Nucleoside diphosphate kinase. | 0.872 |
SMAX5B_000426 | SMAX5B_011034 | ENSSMAP00000006209 | ENSSMAP00000012015 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Putative ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. | 0.904 |
SMAX5B_000426 | SMAX5B_012364 | ENSSMAP00000006209 | ENSSMAP00000021145 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Putative bifunctional purine biosynthesis protein PURH. | 0.851 |
SMAX5B_000426 | SMAX5B_019619 | ENSSMAP00000006209 | ENSSMAP00000023479 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Putative adenylate kinase 9 isoform 2. | 0.873 |
SMAX5B_000426 | SMAX5B_021133 | ENSSMAP00000006209 | ENSSMAP00000012287 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Putative ectonucleoside triphosphate diphosphohydrolase 6 isoform 2; Belongs to the GDA1/CD39 NTPase family. | 0.853 |
SMAX5B_000426 | SMAX5B_022540 | ENSSMAP00000006209 | ENSSMAP00000006338 | Putative ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. | Putative guanylate kinase-like. | 0.842 |