STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF516Putative zinc finger protein 516. (1145 aa)    
Predicted Functional Partners:
SMAX5B_014699
Putative PR domain zinc finger protein 16.
    
0.937
SMAX5B_000441
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.933
SMAX5B_019619
Putative adenylate kinase 9 isoform 2.
    
  0.873
KDM1B
Putative lysine-specific histone demethylase 1B.
    
  0.844
SMAX5B_007298
Uncharacterized protein.
   
  0.680
SMAX5B_018326
Putative BRCA1-associated RING domain protein 1 isoform 2.
    
 0.636
SMAX5B_004819
Putative receptor-interacting serine/threonine-protein kinase 4.
    
  0.633
SMAX5B_001802
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.597
YTHDC2
Putative ATP-dependent RNA helicase YTHDC2.
    
  0.581
SMAX5B_018399
Putative thioredoxin domain-containing protein 3-like; Belongs to the NDK family.
    
 0.571
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.