STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_017559Putative plasminogen activator inhibitor 1; Belongs to the serpin family. (396 aa)    
Predicted Functional Partners:
SMAX5B_010290
Putative tissue-type plasminogen activator.
  
 0.980
SMAX5B_013447
Putative vitronectin.
   
 0.973
SMAX5B_012733
Putative vitronectin-like.
   
 0.973
SMAX5B_018069
Putative tissue-type plasminogen activator-like isoform 2; Belongs to the peptidase S1 family.
  
 0.966
SMAX5B_020518
Putative tissue-type plasminogen activator-like.
  
 0.966
SMAX5B_001789
Putative type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.881
SMAX5B_000212
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.815
SMAX5B_001940
Putative leukocyte elastase inhibitor-like isoform 2; Belongs to the serpin family.
  
  
0.773
SMAX5B_002932
Putative leukocyte elastase inhibitor-like; Belongs to the serpin family.
  
  
0.771
SMAX5B_001586-2
Leukocyte elastase inhibitor; Belongs to the serpin family.
  
  
0.770
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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