STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_003400Putative thrombomodulin-like. (354 aa)    
Predicted Functional Partners:
SMAX5B_002120
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.986
SMAX5B_000212
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
    
 0.741
SMAX5B_007298
Uncharacterized protein.
   
  0.712
SMAX5B_007980
Putative zinc finger protein 408-like.
    
  0.707
SMAX5B_000611
Uncharacterized protein; Belongs to the peptidase S1 family.
    
 0.703
ENSSMAP00000016567
annotation not available
    
 0.703
SMAX5B_018069
Putative tissue-type plasminogen activator-like isoform 2; Belongs to the peptidase S1 family.
   
 0.699
SMAX5B_010290
Putative tissue-type plasminogen activator.
   
 0.699
SMAX5B_020518
Putative tissue-type plasminogen activator-like.
   
 0.699
PTK7
Putative inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
  0.688
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.