node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMAX5B_000212 | SMAX5B_002120 | ENSSMAP00000007673 | ENSSMAP00000000080 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.938 |
SMAX5B_000212 | SMAX5B_012058 | ENSSMAP00000007673 | ENSSMAP00000010820 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | Trypsinogen H1 3a1; Belongs to the peptidase S1 family. | 0.543 |
SMAX5B_000212 | SMAX5B_017015 | ENSSMAP00000007673 | ENSSMAP00000016903 | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.900 |
SMAX5B_002120 | SMAX5B_000212 | ENSSMAP00000000080 | ENSSMAP00000007673 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.938 |
SMAX5B_002120 | SMAX5B_012058 | ENSSMAP00000000080 | ENSSMAP00000010820 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Trypsinogen H1 3a1; Belongs to the peptidase S1 family. | 0.549 |
SMAX5B_002120 | SMAX5B_016471 | ENSSMAP00000000080 | ENSSMAP00000030598 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Putative guanine nucleotide-binding protein subunit alpha-14-like. | 0.531 |
SMAX5B_002120 | SMAX5B_016552 | ENSSMAP00000000080 | ENSSMAP00000030611 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Guanine nucleotide-binding protein G(Q) subunit alpha. | 0.531 |
SMAX5B_002120 | SMAX5B_017015 | ENSSMAP00000000080 | ENSSMAP00000016903 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.994 |
SMAX5B_004407 | SMAX5B_011453 | ENSSMAP00000023536 | ENSSMAP00000034788 | Putative guanine nucleotide-binding protein subunit alpha-13. | Putative guanine nucleotide-binding protein subunit alpha-12. | 0.822 |
SMAX5B_004407 | SMAX5B_016471 | ENSSMAP00000023536 | ENSSMAP00000030598 | Putative guanine nucleotide-binding protein subunit alpha-13. | Putative guanine nucleotide-binding protein subunit alpha-14-like. | 0.596 |
SMAX5B_004407 | SMAX5B_016552 | ENSSMAP00000023536 | ENSSMAP00000030611 | Putative guanine nucleotide-binding protein subunit alpha-13. | Guanine nucleotide-binding protein G(Q) subunit alpha. | 0.595 |
SMAX5B_004407 | SMAX5B_017015 | ENSSMAP00000023536 | ENSSMAP00000016903 | Putative guanine nucleotide-binding protein subunit alpha-13. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.909 |
SMAX5B_004407 | SMAX5B_017466 | ENSSMAP00000023536 | ENSSMAP00000010081 | Putative guanine nucleotide-binding protein subunit alpha-13. | Guanine nucleotide-binding protein alpha-13 subunit. | 0.820 |
SMAX5B_004407 | SMAX5B_022284 | ENSSMAP00000023536 | ENSSMAP00000014618 | Putative guanine nucleotide-binding protein subunit alpha-13. | Putative guanine nucleotide-binding protein subunit alpha-11-like. | 0.545 |
SMAX5B_011453 | SMAX5B_004407 | ENSSMAP00000034788 | ENSSMAP00000023536 | Putative guanine nucleotide-binding protein subunit alpha-12. | Putative guanine nucleotide-binding protein subunit alpha-13. | 0.822 |
SMAX5B_011453 | SMAX5B_016471 | ENSSMAP00000034788 | ENSSMAP00000030598 | Putative guanine nucleotide-binding protein subunit alpha-12. | Putative guanine nucleotide-binding protein subunit alpha-14-like. | 0.597 |
SMAX5B_011453 | SMAX5B_016552 | ENSSMAP00000034788 | ENSSMAP00000030611 | Putative guanine nucleotide-binding protein subunit alpha-12. | Guanine nucleotide-binding protein G(Q) subunit alpha. | 0.595 |
SMAX5B_011453 | SMAX5B_017015 | ENSSMAP00000034788 | ENSSMAP00000016903 | Putative guanine nucleotide-binding protein subunit alpha-12. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.896 |
SMAX5B_011453 | SMAX5B_022284 | ENSSMAP00000034788 | ENSSMAP00000014618 | Putative guanine nucleotide-binding protein subunit alpha-12. | Putative guanine nucleotide-binding protein subunit alpha-11-like. | 0.548 |
SMAX5B_011983 | SMAX5B_017015 | ENSSMAP00000010801 | ENSSMAP00000016903 | Trypsinogen Y; Belongs to the peptidase S1 family. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.884 |