IGFBP4 protein (Scophthalmus maximus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IGFBP4

Insulin-like growth factor binding protein 4. (259 aa)

Predicted Functional Partners:

ENSSMAP00000015186

0.821

SMAX5B_003619

0.635

SMAX5B_010640

0.582

SMAX5B_010010

0.431

SMAX5B_002797

0.421

SMAX5B_014713

0.421

SMAX5B_014286

0.417

SMAX5B_006796

0.416

LGR5

0.416

SMAX5B_019017

0.416

Your Current Organism:

Scophthalmus maximus

NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSMAP00000015186	IGFBP4	ENSSMAP00000015186	ENSSMAP00000017539	Insulin-like growth factor 2b.	Insulin-like growth factor binding protein 4.	0.821
ENSSMAP00000015186	SMAX5B_003619	ENSSMAP00000015186	ENSSMAP00000007635	Insulin-like growth factor 2b.	Uncharacterized protein.	0.452
IGFBP4	ENSSMAP00000015186	ENSSMAP00000017539	ENSSMAP00000015186	Insulin-like growth factor binding protein 4.	Insulin-like growth factor 2b.	0.821
IGFBP4	LGR5	ENSSMAP00000017539	ENSSMAP00000011933	Insulin-like growth factor binding protein 4.	Putative leucine-rich repeat-containing G-protein coupled receptor 5.	0.416
IGFBP4	SMAX5B_002797	ENSSMAP00000017539	ENSSMAP00000006538	Insulin-like growth factor binding protein 4.	Putative asporin.	0.421
IGFBP4	SMAX5B_003619	ENSSMAP00000017539	ENSSMAP00000007635	Insulin-like growth factor binding protein 4.	Uncharacterized protein.	0.635
IGFBP4	SMAX5B_006796	ENSSMAP00000017539	ENSSMAP00000006396	Insulin-like growth factor binding protein 4.	Putative relaxin receptor 2.	0.416
IGFBP4	SMAX5B_010010	ENSSMAP00000017539	ENSSMAP00000021816	Insulin-like growth factor binding protein 4.	Putative p53-induced protein with a death domain-like.	0.431
IGFBP4	SMAX5B_010640	ENSSMAP00000017539	ENSSMAP00000008278	Insulin-like growth factor binding protein 4.	Preproinsulin-growth factor I.	0.582
IGFBP4	SMAX5B_014286	ENSSMAP00000017539	ENSSMAP00000009296	Insulin-like growth factor binding protein 4.	Putative prolargin.	0.417
IGFBP4	SMAX5B_014713	ENSSMAP00000017539	ENSSMAP00000011003	Insulin-like growth factor binding protein 4.	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.421
IGFBP4	SMAX5B_019017	ENSSMAP00000017539	ENSSMAP00000015425	Insulin-like growth factor binding protein 4.	Putative relaxin receptor 1.	0.416
LGR5	IGFBP4	ENSSMAP00000011933	ENSSMAP00000017539	Putative leucine-rich repeat-containing G-protein coupled receptor 5.	Insulin-like growth factor binding protein 4.	0.416
LGR5	SMAX5B_006796	ENSSMAP00000011933	ENSSMAP00000006396	Putative leucine-rich repeat-containing G-protein coupled receptor 5.	Putative relaxin receptor 2.	0.596
LGR5	SMAX5B_010010	ENSSMAP00000011933	ENSSMAP00000021816	Putative leucine-rich repeat-containing G-protein coupled receptor 5.	Putative p53-induced protein with a death domain-like.	0.648
LGR5	SMAX5B_014286	ENSSMAP00000011933	ENSSMAP00000009296	Putative leucine-rich repeat-containing G-protein coupled receptor 5.	Putative prolargin.	0.402
LGR5	SMAX5B_019017	ENSSMAP00000011933	ENSSMAP00000015425	Putative leucine-rich repeat-containing G-protein coupled receptor 5.	Putative relaxin receptor 1.	0.626
SMAX5B_002797	IGFBP4	ENSSMAP00000006538	ENSSMAP00000017539	Putative asporin.	Insulin-like growth factor binding protein 4.	0.421
SMAX5B_002797	SMAX5B_014286	ENSSMAP00000006538	ENSSMAP00000009296	Putative asporin.	Putative prolargin.	0.718
SMAX5B_003619	ENSSMAP00000015186	ENSSMAP00000007635	ENSSMAP00000015186	Uncharacterized protein.	Insulin-like growth factor 2b.	0.452