STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSSMAP00000021016WASP actin nucleation promoting factor a. (525 aa)    
Predicted Functional Partners:
SMAX5B_012637
Putative intersectin-2.
    
 0.995
SMAX5B_008282
Putative intersectin-2.
    
 0.995
SMAX5B_008644
Putative intersectin-1-like.
    
 0.991
ENSSMAP00000002370
annotation not available
    
 0.991
ENSSMAP00000034097
WAS/WASL interacting protein family, member 2a.
   
 0.984
SMAX5B_010613
Putative actin-related protein 2-B-like; Belongs to the actin family.
    
 0.979
SMAX5B_015057
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
 0.979
SMAX5B_008765
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.978
SMAX5B_009614
Putative WAS/WASL-interacting protein family member 3-like.
    
 0.976
SMAX5B_021672
Actin-related protein 3; Belongs to the actin family.
    
 0.974
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.