STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S100PEF-hand domain-containing protein. (92 aa)    
Predicted Functional Partners:
SMAX5B_006462
AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.
    
  0.813
SMAX5B_003220
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
  0.793
SMAX5B_015601
Protein S100; Belongs to the S-100 family.
   
0.764
SMAX5B_004732
Annexin.
   
 0.732
ENSSMAP00000008275
Annexin A1a.
   
 0.732
ENSSMAP00000026411
Annexin A2a.
   
 0.732
ENSSMAP00000013939
Adaptor related protein complex 2 subunit beta 1.
    
  0.720
SMAX5B_016490
AP complex subunit beta.
    
  0.720
SMAX5B_010404
Putative cyclin-G-associated kinase-like.
   
 0.676
SMAX5B_000322
Purple acid phosphatase.
   
 0.664
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.