STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
SMAX5B_016578Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)    
Predicted Functional Partners:
SMAX5B_012307
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
 
 
 0.996
SMAX5B_003033
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.961
SMAX5B_005723
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 0.954
SMAX5B_016991
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 0.942
SMAX5B_009965
Putative inositol oxygenase isoform 2.
   
 
 0.920
SMAX5B_001152
Putative hydroxyacid oxidase 2-like.
  
 
 0.915
SMAX5B_001389
Putative hydroxyacid oxidase 1.
  
 
 0.915
SMAX5B_022673
Putative cystathionine gamma-lyase isoform 2.
 
    0.900
SMAX5B_002155
Putative SH3 domain-containing YSC84-like protein 1.
    
   0.897
SMAX5B_017936
Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase cytoplasmic.
    
 0.897
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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