STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_017784E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (341 aa)    
Predicted Functional Partners:
SMAX5B_006434
Putative calcyclin-binding protein isoform 2.
    
 0.983
SMAX5B_011937
Catenin beta-1.
    
 0.942
SMAX5B_015859
Catenin beta-1.
    
 0.907
SMAX5B_007767
Putative ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.859
SMAX5B_009815
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.859
SMAX5B_006457
Ubiquitin-conjugating enzyme E2 variant 2.
    
   0.844
SMAX5B_008528
Putative baculoviral IAP repeat-containing protein 6-like.
    
 0.795
SMAX5B_013986
Putative alpha-synuclein-like; Belongs to the synuclein family.
    
 0.788
SMAX5B_018143
Putative ubiquitin-conjugating enzyme E2 E2-like; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.755
SMAX5B_018130
Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.755
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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