STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAX5B_012296Putative E3 SUMO-protein ligase PIAS1-like. (708 aa)    
Predicted Functional Partners:
SMAX5B_015982
Small ubiquitin-related modifier.
    
 0.967
SMAX5B_005752
Putative SUMO-conjugating enzyme UBC9 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.908
ENSSMAP00000020441
Ubiquitin-conjugating enzyme E2Ia.
    
 0.908
SMAX5B_020527
BTB/POZ domain-containing protein KCTD2.
    
 0.903
SMAX5B_001446
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.898
SMAX5B_018177
Small ubiquitin-related modifier.
    
 0.896
SMAX5B_020963
Small ubiquitin-related modifier.
    
 0.896
ENSSMAP00000025116
annotation not available
    
 0.896
SMAX5B_022595
E3 SUMO-protein ligase PIAS4.
    
0.873
SMAX5B_009969
E3 SUMO-protein ligase PIAS1.
  
  
 
0.843
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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