close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH24776.1Thioredoxin reductase. (330 aa)    
Predicted Functional Partners:
AEH25296.1
Protein disulfide oxidoreductase.
 
 
 0.941
AEH24553.1
Cystathionine gamma-lyase.
  
 
 0.922
AEH24593.1
Cystathionine gamma-lyase.
  
 
 0.922
AEH25566.1
nifS protein.
  
 
 0.919
AEH24577.1
Alkyl hydroperoxide reductase subunit c.
  
 
 0.767
AEH24602.1
Peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.767
AEH25353.1
Phosphoadenosine phosphosulfate reductase family protein.
     
 0.760
AEH24412.1
Threonine synthase.
   
 
 0.743
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
  
 0.741
AEH24775.1
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.647
Your Current Organism:
Pyrococcus yayanosii
NCBI taxonomy Id: 529709
Other names: P. yayanosii CH1, Pyrococcus sp. CH1, Pyrococcus yayanosii CH1, Pyrococcus yayanosii str. CH1, Pyrococcus yayanosii strain CH1
Server load: low (24%) [HD]