node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIC46859.1 | hisD | Rhola_00000280 | Rhola_00008470 | Histidine ammonia-lyase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.923 |
AIC47556.1 | AIC47759.1 | Rhola_00007520 | Rhola_00009590 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | Archaeal fructose-1,6-bisphosphatase-like proteins of inositol monophosphatase family. | 0.471 |
AIC47556.1 | hisA | Rhola_00007520 | Rhola_00004890 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.988 |
AIC47556.1 | hisB | Rhola_00007520 | Rhola_00004870 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | Imidazoleglycerol-phosphate dehydratase. | 0.993 |
AIC47556.1 | hisC | Rhola_00007520 | Rhola_00004860 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.989 |
AIC47556.1 | hisD | Rhola_00007520 | Rhola_00008470 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.995 |
AIC47556.1 | hisE | Rhola_00007520 | Rhola_00007510 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | phosphoribosyl-ATP pyrophosphatase. | 0.999 |
AIC47556.1 | hisF | Rhola_00007520 | Rhola_00007530 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.998 |
AIC47556.1 | hisH | Rhola_00007520 | Rhola_00004880 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.985 |
AIC47556.1 | hisI | Rhola_00007520 | Rhola_00007540 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.997 |
AIC47759.1 | AIC47556.1 | Rhola_00009590 | Rhola_00007520 | Archaeal fructose-1,6-bisphosphatase-like proteins of inositol monophosphatase family. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | 0.471 |
AIC47759.1 | hisA | Rhola_00009590 | Rhola_00004890 | Archaeal fructose-1,6-bisphosphatase-like proteins of inositol monophosphatase family. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.516 |
AIC47759.1 | hisB | Rhola_00009590 | Rhola_00004870 | Archaeal fructose-1,6-bisphosphatase-like proteins of inositol monophosphatase family. | Imidazoleglycerol-phosphate dehydratase. | 0.434 |
AIC47759.1 | hisC | Rhola_00009590 | Rhola_00004860 | Archaeal fructose-1,6-bisphosphatase-like proteins of inositol monophosphatase family. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.916 |
AIC47759.1 | hisD | Rhola_00009590 | Rhola_00008470 | Archaeal fructose-1,6-bisphosphatase-like proteins of inositol monophosphatase family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.926 |
AIC47759.1 | hisF | Rhola_00009590 | Rhola_00007530 | Archaeal fructose-1,6-bisphosphatase-like proteins of inositol monophosphatase family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.482 |
AIC47759.1 | hisH | Rhola_00009590 | Rhola_00004880 | Archaeal fructose-1,6-bisphosphatase-like proteins of inositol monophosphatase family. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.436 |
hisA | AIC47556.1 | Rhola_00004890 | Rhola_00007520 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). | 0.988 |
hisA | AIC47759.1 | Rhola_00004890 | Rhola_00009590 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Archaeal fructose-1,6-bisphosphatase-like proteins of inositol monophosphatase family. | 0.516 |
hisA | hisB | Rhola_00004890 | Rhola_00004870 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Imidazoleglycerol-phosphate dehydratase. | 0.998 |