Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Psta_0179Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: bmu:Bmul_5088 two component LuxR family transcriptional regulator. (213 aa)    
Predicted Functional Partners:
Psta_1198
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; KEGG: mag:amb3654 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: MCP methyltransferase CheR-type; CheB methylesterase; histidine kinase dimerisation and phosphoacceptor region; PAS fold-4 domain protein; ATP- binding region ATPase domain protein; PAS fold domain protein; SMART: MCP methyltransferase CheR-type; PAC repeat- containing protein; ATP-binding region ATPase domain protein; PAS domain containing protein.
 
 
 0.952
Psta_0178
KEGG: dar:Daro_2995 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; MASE1 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein.
 
 
 0.932
Psta_4289
KEGG: noc:Noc_2452 multisensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; response regulator receiver; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAC repeat-containing protein; histidine kinase A domain protein; PAS domain containing protein.
 
 0.845
Psta_4538
Multi-sensor signal transduction histidine kinase; KEGG: oca:OCAR_7132 sensor protein FixL; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.829
Psta_3069
KEGG: aba:Acid345_1529 MCP methyltransferase, CheR- type; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
      0.778
Psta_3345
KEGG: mrd:Mrad2831_4031 MCP methyltransferase, CheR- type; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
      0.773
Psta_3651
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: bja:blr0279 two-component hybrid sensor and regulator.
 
 
 0.753
Psta_3075
KEGG: bph:Bphy_5692 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.743
Psta_2940
PAS/PAC sensor hybrid histidine kinase; KEGG: ppd:Ppro_0716 signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 
 0.569
Psta_4529
KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Forkhead-associated protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Forkhead-associated protein; PAS domain containing protein.
  
 
0.527
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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