STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Psta_0338HhH-GPD family protein; Adenine glycosylase active on G-A mispairs. (398 aa)    
Predicted Functional Partners:
Psta_2410
PFAM: Endonuclease/exonuclease/phosphatase; SMART: Deoxyribonuclease I-like; KEGG: predicted protein; K01150 deoxyribonuclease I.
  
 
 0.876
Psta_0339
PFAM: peptidase S9A prolyl oligopeptidase domain protein beta-propeller; peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: slo:Shew_1522 prolyl oligopeptidase.
       0.538
Psta_3745
TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S- methyltransferase DNA binding; KEGG: mlo:mlr2526 methylated-DNA-protein-cystein methyltransferase.
 
   
 0.490
Psta_1042
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.467
Psta_1012
PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding class 1; KEGG: nis:NIS_1287 family X DNA polymerase IV.
    
 
 0.444
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
  
 0.439
Psta_1707
Transcriptional regulator, AraC family; KEGG: rso:RSc2570 bifunctional methylated-DNA-- protein-cysteine methyltransferase/O-6-methylguanine-DNA transcription regulator; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S- methyltransferase DNA binding; Ada metal-binding domain protein; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type.
     
 0.436
Psta_3409
Hypothetical protein; KEGG: pde:Pden_0970 DNA polymerase III, beta subunit.
    
 
 0.427
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
  
0.408
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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