Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
Psta_0576KEGG: mxa:MXAN_3119 hypothetical protein. (346 aa)    
Predicted Functional Partners:
Psta_2287
KEGG: xca:xccb100_3597 hypothetical protein.
 
     0.708
Psta_0577
PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: bbt:BBta_1644 putative thiamine pyrophosphate- requiring enzyme; Belongs to the TPP enzyme family.
       0.535
Psta_1313
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
      0.514
Psta_0575
PFAM: Cupin 2 conserved barrel domain protein; KEGG: dar:Daro_1904 cupin region.
       0.423
Psta_2696
KEGG: sus:Acid_6438 hypothetical protein.
  
     0.413
Psta_4061
KEGG: saz:Sama_1061 hypothetical protein.
  
     0.409
Psta_2494
PFAM: SNARE associated Golgi protein; KEGG: scl:sce5352 hypothetical protein.
  
     0.406
Psta_2031
PFAM: putative thiol-disulphide oxidoreductase DCC; KEGG: ppd:Ppro_0121 putative thiol-disulphide oxidoreductase DCC.
  
     0.401
Psta_0578
PFAM: N-formylglutamate amidohydrolase; KEGG: hypothetical gene supported by CR386744.
       0.400
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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