Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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Psta_0729PAS modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; KEGG: ank:AnaeK_1886 two component, sigma54 specific, transcriptional regulator, fis family. (482 aa)    
Predicted Functional Partners:
Psta_2523
TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; KEGG: bba:Bd0843 RNA polymerase sigma-54 factor.
 
   
 0.832
Psta_0728
Hypothetical protein.
       0.746
Psta_0363
Sigma 54 interacting domain protein; PFAM: regulator of RNA terminal phosphate cyclase; sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: mxa:MXAN_4983 sigma-54 dependent transcriptional regulator RtcR.
  
     0.524
Psta_1198
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; KEGG: mag:amb3654 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: MCP methyltransferase CheR-type; CheB methylesterase; histidine kinase dimerisation and phosphoacceptor region; PAS fold-4 domain protein; ATP- binding region ATPase domain protein; PAS fold domain protein; SMART: MCP methyltransferase CheR-type; PAC repeat- containing protein; ATP-binding region ATPase domain protein; PAS domain containing protein.
  
  
 0.479
nuoN
Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
       0.449
Psta_0731
KEGG: gsu:GSU0350 NADH dehydrogenase I, M subunit; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I).
       0.449
Psta_0732
KEGG: mxa:MXAN_1082 NADH dehydrogenase I, L subunit; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein.
       0.449
Psta_0819
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: ammonium transporter; PAS sensor protein; PFAM: Rh family protein/ammonium transporter; ATP- binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; response regulator receiver.
     
 0.443
Psta_0727
Protein of unknown function DUF59; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
     
 0.434
Psta_2940
PAS/PAC sensor hybrid histidine kinase; KEGG: ppd:Ppro_0716 signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
  
  
 0.427
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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