Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Psta_1114Hypothetical protein. (430 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.871
Psta_1609
KEGG: Ser/Thr protein phosphatase.
   
 0.855
Psta_1253
KEGG: afw:Anae109_3313 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SMART: cyclic nucleotide-binding.
    
 0.842
Psta_3991
PFAM: RNA polymerase alpha subunit domain protein; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sde:Sde_0984 DNA-directed RNA polymerase subunit alpha.
   
 0.790
Psta_2578
Hypothetical protein; KEGG: pna:Pnap_3726 methyltransferase type 12.
    
 0.789
Psta_3418
PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: dar:Daro_2024 peptidase S1C, Do.
   
 0.748
Psta_0641
PFAM: Ankyrin; SMART: Ankyrin; KEGG: smt:Smal_3964 hypothetical protein.
  
 0.693
Psta_0755
KEGG: dal:Dalk_3089 hypothetical protein.
  
 0.693
Psta_1505
KEGG: hypothetical protein.
  
 0.693
Psta_1901
Phosphoglycerate kinase; KEGG: hypothetical protein; K00927 phosphoglycerate kinase.
    
   0.693
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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