STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpFPFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: gbm:Gbem_1960 N- (5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (238 aa)    
Predicted Functional Partners:
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: trpC; indole-3-glycerol-phosphate synthase; K01609 indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.995
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.995
Psta_2632
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: bbr:BB4627 anthranilate synthase component II.
  
 0.991
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.980
trpF-2
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: lch:Lcho_3196 N- (5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family.
  
  
  0.972
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
  
 0.961
Psta_2707
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: tgr:Tgr7_2801 anthranilate synthase component II.
  
 0.947
Psta_2633
PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; KEGG: msl:Msil_2398 para-aminobenzoate synthase, subunit I.
  
 0.940
Psta_0841
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: glo:Glov_2150 chorismate mutase.
 
  
 0.655
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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