STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Psta_2169PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: pca:Pcar_2858 pyruvate decarboxylase. (565 aa)    
Predicted Functional Partners:
Psta_2168
Glucosamine-6-phosphate deaminase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: vei:Veis_1394 glucosamine-6-phosphate deaminase.
     
 0.506
Psta_0841
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: glo:Glov_2150 chorismate mutase.
  
   
 0.497
Psta_0847
Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
   
  
 0.487
Psta_0488
KEGG: gsu:GSU1643 GGDEF/response regulator receiver domain-containing protein; TIGRFAM: diguanylate cyclase; PFAM: CBS domain containing protein; GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver.
   
   0.434
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.434
Psta_1738
TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase/squalene oxidase; KEGG: aba:Acid345_1740 squalene cyclase.
  
     0.433
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.429
Psta_0819
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: ammonium transporter; PAS sensor protein; PFAM: Rh family protein/ammonium transporter; ATP- binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; response regulator receiver.
  
 
 
 0.418
Psta_4688
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: sfu:Sfum_3022 acetolactate synthase, small subunit.
 
  
 0.418
Psta_0225
KEGG: pca:Pcar_2082 RND superfamily exporter.
  
     0.416
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.