STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Psta_2386PFAM: periplasmic binding protein; KEGG: sus:Acid_0126 hypothetical protein. (314 aa)    
Predicted Functional Partners:
Psta_2387
Hypothetical protein; KEGG: trans-sialidase.
  
  
 0.723
nfo
Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
 
      0.671
Psta_2388
KEGG: ank:AnaeK_0667 hypothetical protein.
       0.655
Psta_3967
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bid:Bind_2520 binding-protein-dependent transport systems inner membrane component.
   
  
 0.605
Psta_1519
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.519
Psta_2389
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: acp:A2cp1_0670 ABC transporter related.
     
 0.486
Psta_4644
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: ppd:Ppro_3374 uroporphyrin-III C- methyltransferase.
     
 0.446
Psta_2151
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase; Hydantoinaseoxoprolinase domain protein; Hydantoinase/oxoprolinase; KEGG: dal:Dalk_4188 5-oxoprolinase (ATP- hydrolyzing).
     
 0.440
Psta_1878
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.434
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
     
 0.433
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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