Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Psta_2485KEGG: hsm:HSM_0412 hypothetical protein. (287 aa)    
Predicted Functional Partners:
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
     0.802
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.636
Psta_2486
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
       0.553
Psta_3891
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sfu:Sfum_1981 xylose isomerase domain protein TIM barrel.
  
     0.517
Psta_2484
PFAM: S23 ribosomal protein; KEGG: tbd:Tbd_0653 hypothetical protein.
       0.498
Psta_1719
PFAM: amidohydrolase 2; KEGG: sus:Acid_3067 amidohydrolase 2.
  
     0.479
Psta_3456
KEGG: hypothetical protein.
  
     0.458
Psta_0896
TIGRFAM: heme-binding protein; KEGG: sus:Acid_3123 putative heme-binding protein.
  
    0.422
Psta_4234
KEGG: sus:Acid_6537 hypothetical protein.
  
     0.420
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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