Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Psta_2579PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2127 AMP-dependent synthetase and ligase. (564 aa)    
Predicted Functional Partners:
Psta_2578
Hypothetical protein; KEGG: pna:Pnap_3726 methyltransferase type 12.
  
  
 0.783
Psta_2580
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: rpt:Rpal_2548 acyl-CoA dehydrogenase domain protein.
 
 
 0.751
Psta_4144
PFAM: ubiquitin-conjugating protein E2; KEGG: hypothetical protein.
    
  0.748
Psta_4148
PFAM: ubiquitin-conjugating protein E2; KEGG: hypothetical protein; K10576 ubiquitin- conjugating enzyme E2 H.
    
  0.748
Psta_3650
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: scl:sce7626 Acyl-CoA dehydrogenase.
 
 0.712
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.706
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
 
 0.704
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.704
Psta_0990
KEGG: scl:sce3990 putative isovaleryl-CoA dehydrogenase protein.
  
 0.674
Psta_4641
PFAM: Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: mxa:MXAN_3020 hypothetical protein.
    
 0.541
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.