Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Psta_3072KEGG: pzu:PHZ_c3236 methyl-accepting chemotaxis protein McpH; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: chemotaxis sensory transducer; PAC repeat- containing protein; histidine kinase HAMP region domain protein; PAS domain containing protein. (585 aa)    
Predicted Functional Partners:
Psta_2067
CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; SMART: response regulator receiver; Hpt domain protein; ATP-binding region ATPase domain protein; CheW domain protein; KEGG: dps:DP2642 Che family two-component system sensory/regulatory protein.
 
 0.996
Psta_3073
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: aba:Acid345_1525 CheW protein.
 
 0.996
Psta_3074
PFAM: CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; ATP- binding region ATPase domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: aba:Acid345_1524 CheA signal transduction histidine kinases.
 
 0.993
Psta_1198
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; KEGG: mag:amb3654 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: MCP methyltransferase CheR-type; CheB methylesterase; histidine kinase dimerisation and phosphoacceptor region; PAS fold-4 domain protein; ATP- binding region ATPase domain protein; PAS fold domain protein; SMART: MCP methyltransferase CheR-type; PAC repeat- containing protein; ATP-binding region ATPase domain protein; PAS domain containing protein.
  
 0.992
Psta_3341
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: aba:Acid345_1525 CheW protein.
 
 0.992
Psta_2068
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: dol:Dole_0989 CheW protein.
 
 0.991
Psta_3069
KEGG: aba:Acid345_1529 MCP methyltransferase, CheR- type; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
 
 0.990
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.990
Psta_3316
PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: lip:LI1170 chemotaxis signal transduction protein.
 
 0.989
Psta_3340
PFAM: CheW domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; ATP- binding region ATPase domain protein; SMART: CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: aba:Acid345_1524 CheA signal transduction histidine kinases.
 
 0.984
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.