Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Psta_4094Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; SMART: response regulator receiver; KEGG: ppd:Ppro_3079 two component, sigma54 specific, fis family transcriptional regulator. (511 aa)    
Predicted Functional Partners:
Psta_4095
Histidine kinase; KEGG: mmr:Mmar10_2521 periplasmic sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver.
  
 
 0.805
Psta_2523
TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; KEGG: bba:Bd0843 RNA polymerase sigma-54 factor.
 
   
 0.770
Psta_2940
PAS/PAC sensor hybrid histidine kinase; KEGG: ppd:Ppro_0716 signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.732
Psta_0178
KEGG: dar:Daro_2995 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; MASE1 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein.
 
 
 
 0.525
Psta_0819
KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; TIGRFAM: ammonium transporter; PAS sensor protein; PFAM: Rh family protein/ammonium transporter; ATP- binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; response regulator receiver.
  
 
 0.514
Psta_0928
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: scl:sce2560 sigma-54 dependent DNA-binding response regulator.
  
     0.514
Psta_1198
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; KEGG: mag:amb3654 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: MCP methyltransferase CheR-type; CheB methylesterase; histidine kinase dimerisation and phosphoacceptor region; PAS fold-4 domain protein; ATP- binding region ATPase domain protein; PAS fold domain protein; SMART: MCP methyltransferase CheR-type; PAC repeat- containing protein; ATP-binding region ATPase domain protein; PAS domain containing protein.
  
 
 0.498
Psta_3776
TIGRFAM: flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; KEGG: cff:CFF8240_1512 flagellar motor switch protein FliM.
  
  
 0.491
Psta_4538
Multi-sensor signal transduction histidine kinase; KEGG: oca:OCAR_7132 sensor protein FixL; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 
 0.482
Psta_4093
Hypothetical protein.
       0.476
Your Current Organism:
Pirellula staleyi
NCBI taxonomy Id: 530564
Other names: P. staleyi DSM 6068, Pirellula staleyi ATCC 27377, Pirellula staleyi DSM 6068, Pirellula staleyi str. DSM 6068, Pirellula staleyi strain DSM 6068
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